| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GFM2 (520-779) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:4000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GFM2 |
| Gene ID: |
84340 |
| Uniprot ID: |
RRF2M_HUMAN |
| Immunogen Region: |
520-779 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 520-779 of human GFM2 (NP_115756.2). |
| Immunogen Sequence: |
KVRLDPDSGQTVLCGMGELH IEIIHDRIKREYGLETYLGP LQVAYRETILNSVRATDTLD RTLGDKRHLVTVEVEARPIE TSSVMPVIEFEYAESINEGL LKVSQEAIENGIHSACLQGP LLGSPIQDVAITLHSLTIHP GTSTTMISACVSRCVQKALK KADKQVLEPLMNLEVTVARD YLSPVLADLAQRRGNIQEIQ TRQDNKVVIGFVPLAEIMGY STVLRTLTSGSATFALELS |
| Tissue Specificity | Widely expressed. |
| Function | Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. Promotes mitochondrial ribosome recycling by dissolution of intersubunit contacts. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation. |
| Protein Name | Ribosome-Releasing Factor 2 - MitochondrialRrf2mtElongation Factor G 2 - MitochondrialEf-G2mtMef-G 2Elongation Factor G2Hefg2 |
| Database Links | Reactome: R-HSA-5419276 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Ribosome-Releasing Factor 2 - Mitochondrial antibodyAnti-Rrf2mt antibodyAnti-Elongation Factor G 2 - Mitochondrial antibodyAnti-Ef-G2mt antibodyAnti-Mef-G 2 antibodyAnti-Elongation Factor G2 antibodyAnti-Hefg2 antibodyAnti-GFM2 antibodyAnti-EFG2 antibodyAnti-MSTP027 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
