| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GSTT1 |
| Gene ID: | 2952 |
| Uniprot ID: | GSTT1_HUMAN |
| Immunogen Region: | 1-240 |
| Immunogen Sequence: | MGLELYLDLLSQPCRAVYIF AKKNDIPFELRIVDLIKGQH LSDAFAQVNPLKKVPALKDG DFTLTESVAILLYLTRKYKV PDYWYPQDLQARARVDEYLA WQHTTLRRSCLRALWHKVMF PVFLGEPVSPQTLAATLAEL DVTLQLLEDKFLQNKAFLTG PHISLADLVAITELMHPVGA GCQVFEGRPKLATWRQRVEA AVGEDLFQEAHEVILKAKDF PPADPTIKQKLMPWVLAMI |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of GSTT1 (NP_000844.2). |
| Tissue Specificity | Found in erythrocyte. Expressed at low levels in liver. In lung, expressed at low levels in club cells and ciliated cells at the alveolar/bronchiolar junction. Absent from epithelial cells of larger bronchioles. |
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide. |
| Protein Name | Glutathione S-Transferase Theta-1Gst Class-Theta-1Glutathione Transferase T1-1 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-9753281 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Glutathione S-Transferase Theta-1 antibodyAnti-Gst Class-Theta-1 antibodyAnti-Glutathione Transferase T1-1 antibodyAnti-GSTT1 antibody |
Information sourced from Uniprot.org
![Immunofluorescence analysis of U-2 OS cells using [KO Validated] NSDHL Rabbit polyclonal antibody (STJ119221) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/98093/381689/STJ119221_1__50370.1713149871.jpg?c=1 "Immunofluorescence analysis of U-2 OS cells using [KO Validated] NSDHL Rabbit polyclonal antibody (STJ119221) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.")
