Anti-HURP antibody

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Product name Anti-HURP antibody
Description Rabbit polyclonal to HURP.
Applications ELISA, WB
Dilution range WB 1:500-1:2000
ELISA 1:40000
Specificity HURP Polyclonal Antibody detects endogenous levels of HURP protein.
Protein Name Disks large-associated protein 5
DAP-5
Discs large homolog 7
Disks large-associated protein DLG7
Hepatoma up-regulated protein
HURP
Immunogen Synthesized peptide derived from human HURP
Immunogen Region 760-840 aa, C-terminal
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB
Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 9787
Gene Symbol DLGAP5
Molecular Weight 95 kDa
Database Links HGNC:16864
OMIM:NA
Alternative Names Disks large-associated protein 5 antibody
DAP-5 antibody
Discs large homolog 7 antibody
Disks large-associated protein DLG7 antibody
Hepatoma up-regulated protein antibody
DLG7 antibody
KIAA0008 antibody
Function Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
Post-translational Modifications Ubiquitinated, leading to its degradation. Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells.
Cellular Localization Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells.
Tissue Specificity Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta.
Swiss-Prot Key Q15398_HUMAN
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