Anti-DLGAP5 antibody (791-840 aa) (STJ93629)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human DLGAP5 at the amino acid range 791-840
General Information
| Short Description | Rabbit polyclonal anti-Disks large-associated protein 5 (791-840 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DLGAP5 |
| Gene ID | 9787 |
| Uniprot ID | DLGP5_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human DLGAP5 at the amino acid range 791-840 |
| Immunogen Region | 791-840 aa |
| Specificity | HURP Polyclonal Antibody detects endogenous levels of HURP protein. |
Additional Info
| Post Translational Modifications | Ubiquitinated, leading to its degradation. Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells. |
| Function | Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells. |
| Protein Name | Disks Large-Associated Protein 5Dap-5Discs Large Homolog 7Disks Large-Associated Protein Dlg7Hepatoma Up-Regulated ProteinHurp |
| Database Links | Reactome: R-HSA-9013508 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonSpindleLocalizes To The Spindle In Mitotic CellsColocalizes With Cdh1 At Sites Of Cell-Cell Contact In Intestinal Epithelial Cells |
| Alternative Antibody Names | Anti-Disks Large-Associated Protein 5 antibodyAnti-Dap-5 antibodyAnti-Discs Large Homolog 7 antibodyAnti-Disks Large-Associated Protein Dlg7 antibodyAnti-Hepatoma Up-Regulated Protein antibodyAnti-Hurp antibodyAnti-DLGAP5 antibodyAnti-DLG7 antibodyAnti-KIAA0008 antibody |
Information sourced from Uniprot.org