Western blot analysis of the lysates from HeLa cells using IL15RA antibody.

Anti-IL15RA antibody (99-148 aa) (STJ93680)

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STJ93680
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Interleukin-15 receptor subunit alpha (99-148 aa) for use in WB and ELISA in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-1:2000
ELISA 1:40000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:IL15RA
Gene ID:3601
Uniprot ID:I15RA_HUMAN
Immunogen:The antiserum was produced against synthesized peptide derived from the human IL15RA at the amino acid range 99-148
Immunogen Region:99-148 aa
Specificity:IL-15R Alpha Polyclonal Antibody detects endogenous levels of IL-15R Alpha protein.
Post Translational Modifications N-glycosylated and O-glycosylated. A soluble form (sIL-15RA) arises from proteolytic shedding of the membrane-anchored receptor. It also binds IL-15 and thus interferes with IL-15 binding to the membrane receptor.
Function High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. In neutrophils, binds and activates kinase SYK in response to IL15 stimulation. In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner. Expression of different isoforms may alter or interfere with signal transduction. Isoform 5: Does not bind IL15. Isoform 6: Does not bind IL15. Isoform 7: Does not bind IL15. Isoform 8: Does not bind IL15.
Protein Name Interleukin-15 Receptor Subunit Alpha
Il-15 Receptor Subunit Alpha
Il-15r-Alpha
Il-15ra
Cd Antigen Cd215 Cleaved Into - Soluble Interleukin-15 Receptor Subunit Alpha
Sil-15 Receptor Subunit Alpha
Sil-15r-Alpha
Sil-15ra
Database Links Reactome: R-HSA-8983432
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Nucleus Membrane
Cell Surface
Mainly Found Associated With The Nuclear Membrane
Isoform 5: Endoplasmic Reticulum Membrane
Golgi Apparatus Membrane
Cytoplasmic Vesicle Membrane
Isoform 5
Isoform 6
Isoform 7 And Isoform 8 Are Associated With Endoplasmic Reticulum
Golgi And Cytoplasmic Vesicles
But Not With The Nuclear Membrane
Isoform 6: Endoplasmic Reticulum Membrane
Isoform 7: Endoplasmic Reticulum Membrane
Isoform 8: Endoplasmic Reticulum Membrane
Soluble Interleukin-15 Receptor Subunit Alpha: Secreted
Extracellular Space
Alternative Antibody Names Anti-Interleukin-15 Receptor Subunit Alpha antibody
Anti-Il-15 Receptor Subunit Alpha antibody
Anti-Il-15r-Alpha antibody
Anti-Il-15ra antibody
Anti-Cd Antigen Cd215 Cleaved Into - Soluble Interleukin-15 Receptor Subunit Alpha antibody
Anti-Sil-15 Receptor Subunit Alpha antibody
Anti-Sil-15r-Alpha antibody
Anti-Sil-15ra antibody
Anti-IL15RA antibody

Information sourced from Uniprot.org

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