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Anti-IL7R antibody

[STJ24192] Download PDF Print Data Sheet

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Product name Anti-IL7R antibody
Short Description Rabbit polyclonal to IL7R
Description The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.
Applications IF, WB
Dilution range WB 1:500 - 1:2000
IF 1:20 - 1:50
Protein Name Interleukin-7 receptor subunit alpha
IL-7 receptor subunit alpha
IL-7R subunit alpha
IL-7R-alpha
IL-7RA
CDw127
CD antigen CD127
Immunogen Recombinant protein of human IL7R
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 3575
Gene Symbol IL7R
Molecular Weight 51.581 kDa
Database Links HGNC:6024
OMIM:146661
Reactome:R-HSA-1266695
Alternative Names Interleukin-7 receptor subunit alpha antibody
IL-7 receptor subunit alpha antibody
IL-7R subunit alpha antibody
IL-7R-alpha antibody
IL-7RA antibody
CDw127 antibody
CD antigen CD127 antibody
Function Receptor for interleukin-7, Also acts as a receptor for thymic stromal lymphopoietin (TSLP)
Post-translational Modifications N-glycosylated IL-7Ralpha binds IL7 300-fold more tightly than the unglycosylated form,
Cellular Localization Cell membrane
Swiss-Prot Key P16871
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