Anti-IVD antibody (33-200) (STJ117476)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal IVD (33-200) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IVD |
| Gene ID | 3712 |
| Uniprot ID | IVD_HUMAN |
| Immunogen Region | 33-200 |
| Immunogen Sequence | HSLLPVDDAINGLSEEQRQL RQTMAKFLQEHLAPKAQEID RSNEFKNLREFWKQLGNLGV LGITAPVQYGGSGLGYLEHV LVMEEISRASGAVGLSYGAH SNLCINQLVRNGNEAQKEKY LPKLISGEYIGALAMSEPNA GSDVVSMKLKAEKKGNHYIL NGNKFWIT |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 33-200 of human IVD (NP_002216.2). |
Additional Info
| Function | Catalyzes the conversion of isovaleryl-CoA/3-methylbutanoyl-CoA to 3-methylbut-2-enoyl-CoA as an intermediate step in the leucine (Leu) catabolic pathway. To a lesser extent, is also able to catalyze the oxidation of other saturated short-chain acyl-CoA thioesters as pentanoyl-CoA, hexenoyl-CoA and butenoyl-CoA. |
| Protein Name | Isovaleryl-Coa Dehydrogenase - MitochondrialIvdButyryl-Coa Dehydrogenase |
| Database Links | Reactome: R-HSA-70895Reactome: R-HSA-9914355 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Isovaleryl-Coa Dehydrogenase - Mitochondrial antibodyAnti-Ivd antibodyAnti-Butyryl-Coa Dehydrogenase antibodyAnti-IVD antibody |
Information sourced from Uniprot.org