Anti-JMJD1C antibody (354-448) (STJ11103184)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal JMJD1C (354-448) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | JMJD1C |
| Gene ID | 221037 |
| Uniprot ID | JHD2C_HUMAN |
| Immunogen Region | 354-448 |
| Immunogen Sequence | KPEEDEKKLNMKRLRTDNVS DFSESSDSENSNKRIIDNSS EQKPENELKNKNTSKINGEE GKPHNNEKAGEETLKNSQPP WDQIQEDKKHEEAEK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 354-448 of human JMJD1C (NP_116165.1). |
Additional Info
| Function | Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes. |
| Protein Name | Probable Jmjc Domain-Containing Histone Demethylation Protein 2cJumonji Domain-Containing Protein 1cThyroid Receptor-Interacting Protein 8Tr-Interacting Protein 8Trip-8 |
| Database Links | Reactome: R-HSA-983231 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Probable Jmjc Domain-Containing Histone Demethylation Protein 2c antibodyAnti-Jumonji Domain-Containing Protein 1c antibodyAnti-Thyroid Receptor-Interacting Protein 8 antibodyAnti-Tr-Interacting Protein 8 antibodyAnti-Trip-8 antibodyAnti-JMJD1C antibodyAnti-JHDM2C antibodyAnti-KIAA1380 antibodyAnti-TRIP8 antibody |
Information sourced from Uniprot.org