• Anti-Keratin 8+18 antibody [C-51] (STJ16101019)

Anti-Keratin 8+18 antibody [C-51] (STJ16101019)

SKU:
STJ16101019

£264.50 - £1,251.50
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Host: Mouse
Applications: FC/WB/IF/IHC
Reactivity: Cow/Human/Monkey/Pig/Sheep
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Keratin 8+18 is suitable for use in Flow Cytometry, Western Blot, Immunofluorescence and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: C-51
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: PBS with 0.02% Sodium Azide.
Purification: Affinity purified from tissue culture.
Concentration: Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL.
Dilution Range: Flow Cytometry (1-2 µg/million cells in 0.1 ml, fix cells in 4% PFA for 10 min, at 4°C C, permeabilize with 0, 2% saponin or digitonin for 15 min, at 4°C). Immunoblotting (1-2 µg/ml). Immunofluorescence (1-2 µg/ml). Immunohistology (2-4 µg/ml for 30
Storage Instruction: Store for up to 1 year at 2-8°C upon receipt.
Immunogen: A BALB/c mouse was immunized with a cytoskeleton preparation from HeLa cells. Fusion Partner: Sp2/0.
Background C-51 reacts with keratin 8 (52.5 kDa) + 18 (45 kDa) polypeptides and recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained

Information sourced from Uniprot.org

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