Anti-KRT13 Antibody

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Product name Anti-KRT13 Antibody
Short Description Rabbit polyclonal against KRT13
Description The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Keratin
type I cytoskeletal 13
Cytokeratin-13
CK-13
Keratin-13
K13
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 269-458 of human KRT13 (NP_705694.2).
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 3860
Gene Symbol KRT13
Molecular Weight 49.588 kDa
Database Links HGNC:6415
OMIM:148065
Reactome:R-HSA-6805567
Alternative Names Keratin
type I cytoskeletal 13
Cytokeratin-13
CK-13
Keratin-13
K13
Post-translational Modifications O-glycosylated
Tissue Specificity Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta
Swiss-Prot Key P13646
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