Anti-KRT13 antibody

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Product name Anti-KRT13 antibody
Short Description Rabbit polyclonal against KRT13
Description The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21. 2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described.
Applications WB
Dilution range WB 1:500-1:2000
Protein Name Keratin-Type I Cytoskeletal 13
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 269-458 of human KRT13 (NP_705694. 2).
Storage Instruction Store at-20°C and avoid freeze-thaw cycles.
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 3860
Gene Symbol KRT13
Molecular Weight Calculated: 38kDa/45kDa/49kDa. Observed: 50kDa
Database Links Reactome: R-HSA-6805567
Alternative Names Anti-Keratin-Type I Cytoskeletal 13 antibody
Anti-Cytokeratin-13 antibody
Anti-Ck-13 antibody
Anti-Keratin-13 antibody
Anti-K13 antibody
Anti-KRT13 antibody
Post-translational Modifications O-glycosylated.glycans consist of single N-acetylglucosamine residues.
Tissue Specificity Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.
Swiss-Prot Key K1C13_HUMAN
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