| Short Description : | Rabbit polyclonal anti-Lipopolysaccharide-binding protein (221-270 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA/IHC |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LBP |
| Gene ID: | 3929 |
| Uniprot ID: | LBP_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human LBP at the amino acid range 221-270 |
| Immunogen Region: | 221-270 aa |
| Specificity: | LBP Polyclonal Antibody detects endogenous levels of LBP protein. |
| Function | Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide. |
| Protein Name | Lipopolysaccharide-Binding ProteinLbp |
| Database Links | Reactome: R-HSA-166016Reactome: R-HSA-166020Reactome: R-HSA-5686938Reactome: R-HSA-6785807 |
| Cellular Localisation | SecretedCytoplasmic Granule MembraneMembrane-Associated In Polymorphonuclear Leukocytes (Pmn) Granules |
| Alternative Antibody Names | Anti-Lipopolysaccharide-Binding Protein antibodyAnti-Lbp antibodyAnti-LBP antibody |
Information sourced from Uniprot.org
