| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phosphatidate phosphatase LPIN2 (220-300 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LPIN2 |
| Gene ID: | 9663 |
| Uniprot ID: | LPIN2_HUMAN |
| Immunogen Region: | 220-300 aa |
| Specificity: | LPIN2 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 220-300 |
| Function | Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Plays important roles in controlling the metabolism of fatty acids at different levels. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism. |
| Protein Name | Phosphatidate Phosphatase Lpin2 Lipin-2 |
| Database Links | Reactome: R-HSA-1483191 Reactome: R-HSA-1483213 Reactome: R-HSA-4419969 Reactome: R-HSA-75109 |
| Cellular Localisation | Nucleus Cytoplasm Cytosol Endoplasmic Reticulum Membrane Translocates To Endoplasmic Reticulum Membrane With Increasing Levels Of Oleate |
| Alternative Antibody Names | Anti-Phosphatidate Phosphatase Lpin2 antibody Anti-Lipin-2 antibody Anti-LPIN2 antibody Anti-KIAA0249 antibody |
Information sourced from Uniprot.org