Anti-LRRC7 antibody (730-890) (STJ115080)

Name: Anti-LRRC7 antibody (730-890) (STJ115080)
SKU: STJ115080
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ115080

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Short Description	Rabbit polyclonal LRRC7 (730-890) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	LRRC7Uniprot ID=LRRC7_HUMAN"
Immunogen Region	730-890
Immunogen Sequence	FPQPLDSKPLLSQREAVPPG NIPQRPDRLPMSDTFTDNWT DGSHYDNTGFVAEETTAENA NSNPLLSSKSRSTSSHGRRP LIRQDRIVGVPLELEQSTHR HTPETEVPPSNPWQNWTRTP SPFEDRTAFPSKLETTPTTS PLPERKEHIKESTEIPSPFS P
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 730-890 of human LRRC7 (NP_065845.1).

Tissue Specificity	Brain-specific. Isoform 3 is ubiquitously expressed.
Function	Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression.
Protein Name	Leucine-Rich Repeat-Containing Protein 7 Densin-180 Densin Protein Lap1
Cellular Localisation	Cytoplasm Postsynaptic Density
Alternative Antibody Names	Anti-Leucine-Rich Repeat-Containing Protein 7 antibody Anti-Densin-180 antibody Anti-Densin antibody Anti-Protein Lap1 antibody Anti-LRRC7 antibody Anti-KIAA1365 antibody Anti-LAP1 antibody

Information sourced from Uniprot.org