Anti-MANBA antibody (18-300) (STJ117484)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MANBA (18-300) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MANBA |
| Gene ID | 4126 |
| Uniprot ID | MANBA_HUMAN |
| Immunogen Region | 18-300 |
| Immunogen Sequence | AAELSYSLRGNWSICNGNGS LELPGAVPGCVHSALFQQGL IQDSYYRFNDLNYRWVSLDN WTYSKEFKIPFEISKWQKVN LILEGVDTVSKILFNEVTIG ETDNMFNRYSFDITNVVRDV NSIELRFQSAVLYAAQQSKA HTRYQVPPDCPPLVQKGECH VNFVRKEQCSFSWDWGPSFP TQGIWKDVRIEAYNICHLNY FTFSPIYDKSAQEWNLEIES TFDVVSSKPVGGQVIVAIP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 18-300 of human MANBA (NP_005899.3). |
Additional Info
| Tissue Specificity | Ubiquitous. Detected in pancreas, kidney and placenta, ands at lower levels in liver, lung, brain, heart and muscle. |
| Function | Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides. |
| Protein Name | Beta-MannosidaseLysosomal Beta A MannosidaseMannanaseMannase |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-8853383 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Beta-Mannosidase antibodyAnti-Lysosomal Beta A Mannosidase antibodyAnti-Mannanase antibodyAnti-Mannase antibodyAnti-MANBA antibodyAnti-MANB1 antibody |
Information sourced from Uniprot.org