| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MGAT5B (616-790) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MGAT5B |
| Gene ID: |
146664 |
| Uniprot ID: |
MGT5B_HUMAN |
| Immunogen Region: |
616-790 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 616-790 of human MGAT5B (NP_653278.2). |
| Immunogen Sequence: |
DPYLPYEYTCEGMLERIHAY IQHQDFCRAPDPALPEAHAP QSPFVLAPNATHLEWARNTS LAPGAWPPAHALRAWLAVPG RACTDTCLDHGLICEPSFFP FLNSQDAFLKLQVPCDSTES EMNHLYPAFAQPGQECYLQK EPLLFSCAGSNTKYRRLCPC RDFRKGQVALCQGCL |
| Tissue Specificity | Predominantly expressed in brain. Expressed in all areas of the adult and fetal brain. Also expressed at much lower levels in testis, spleen and thymus. |
| Function | Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAc-beta1,2-Man-alpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway. |
| Protein Name | Alpha-1 -6-Mannosylglycoprotein 6-Beta-N-Acetylglucosaminyltransferase BAlpha-Mannoside Beta-1 -6-N-Acetylglucosaminyltransferase BGlcnac-T VbGnt-VbHgntvbMannoside Acetylglucosaminyltransferase 5bN-Acetylglucosaminyl-Transferase VbN-Acetylglucosaminyltransferase IxGnt-Ix |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Alpha-1 -6-Mannosylglycoprotein 6-Beta-N-Acetylglucosaminyltransferase B antibodyAnti-Alpha-Mannoside Beta-1 -6-N-Acetylglucosaminyltransferase B antibodyAnti-Glcnac-T Vb antibodyAnti-Gnt-Vb antibodyAnti-Hgntvb antibodyAnti-Mannoside Acetylglucosaminyltransferase 5b antibodyAnti-N-Acetylglucosaminyl-Transferase Vb antibodyAnti-N-Acetylglucosaminyltransferase Ix antibodyAnti-Gnt-Ix antibodyAnti-MGAT5B antibodyAnti-KIAA2008 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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