Anti-mGluR-7 antibody

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Product name Anti-mGluR-7 antibody
Short Description Rabbit polyclonal against mGluR-7
Description Rabbit polyclonal to mGluR-7.
Applications ELISA, IF, IHC, WB
Dilution range WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Specificity mGluR-7 Polyclonal Antibody detects endogenous levels of mGluR-7 protein.
Protein Name Metabotropic glutamate receptor 7
Immunogen Synthesized peptide derived from human mGluR-7
Immunogen Region 840-920 aa, C-terminal
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Note For Research Use Only (RUO).
Validated Application IHC WB
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Concentration 1 mg/ml
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene ID 2917
Gene Symbol GRM7
Molecular Weight 100 kDa
Database Links HGNC:4599
Alternative Names Metabotropic glutamate receptor 7
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Cellular Localization Cell membrane. Multi-pass membrane protein.
Tissue Specificity Expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, and cerebellum. Expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 and isoform 4.
Swiss-Prot Key Q14831_HUMAN
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