| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MKKS (221-570) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MKKS |
| Gene ID: |
8195 |
| Uniprot ID: |
MKKS_HUMAN |
| Immunogen Region: |
221-570 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 221-570 of human MKKS (NP_740754.1). |
| Immunogen Sequence: |
EMSEVQLMRLLPIKKSTALK VALFCTTLSGDTSDTGEGTV VVSYGVSLENAVLDQLLNLG RQLISDHVDLVLCQKVIHPS LKQFLNMHRIIAIDRIGVTL MEPLTKMTGTQPIGSLGSIC PNSYGSVKDVCTAKFGSKHF FHLIPNEATICSLLLCNRND TAWDELKLTCQTALHVLQLT LKEPWALLGGGCTETHLAAY IRHKTHNDPESILKDDECTQ TELQLIAEAFCSALESVVG |
| Tissue Specificity | Widely expressed in adult and fetal tissues. |
| Function | Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis. Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis. |
| Protein Name | Molecular Chaperone MkksBardet-Biedl Syndrome 6 ProteinMckusick-Kaufman/Bardet-Biedl Syndromes Putative Chaperonin |
| Database Links | Reactome: R-HSA-5620922 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCytosolNucleusThe Majority Of The Protein Resides Within The Pericentriolar Material (Pcm)A Proteinaceous Tube Surrounding CentriolesDuring InterphaseThe Protein Is Confined To The Lateral Surfaces Of The Pcm But During Mitosis It Relocalizes Throughout The Pcm And Is Found At The Intercellular BridgeThe Mkss Protein Is Highly Mobile And Rapidly Shuttles Between The Cytosol And Centrosome |
| Alternative Antibody Names | Anti-Molecular Chaperone Mkks antibodyAnti-Bardet-Biedl Syndrome 6 Protein antibodyAnti-Mckusick-Kaufman/Bardet-Biedl Syndromes Putative Chaperonin antibodyAnti-MKKS antibodyAnti-BBS6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
