| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MOK |
| Gene ID: | 5891 |
| Uniprot ID: | MOK_HUMAN |
| Immunogen Region: | 1-230 |
| Immunogen Sequence: | MKNYKAIGKIGEGTFSEVMK MQSLRDGNYYACKQMKQRFE SIEQVNNLREIQALRRLNPH PNILMLHEVVFDRKSGSLAL ICELMDMNIYELIRGRRYPL SEKKIMHYMYQLCKSLDHIH RNGIFHRDVKPENILIKQDV LKLGDFGSCRSVYSKQPYTE YISTRWYRAPECLLTDGFYT YKMDLWSAGCVFYEIASLQP LFPGVNELDQISKIHDVIGT PAQKILTKFK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human MOK (NP_055041.1). |
| Tissue Specificity | Expressed in heart, brain, lung, kidney, and pancreas, and at very low levels in placenta, liver and skeletal muscle. Detected in retina. |
| Post Translational Modifications | Autophosphorylated. |
| Function | Able to phosphorylate several exogenous substrates and to undergo autophosphorylation. Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner. |
| Protein Name | Mapk/Mak/Mrk Overlapping KinaseMok Protein KinaseRenal Tumor Antigen 1Rage-1 |
| Database Links | |
| Cellular Localisation | CytoplasmCell ProjectionCiliumNucleus |
| Alternative Antibody Names | Anti-Mapk/Mak/Mrk Overlapping Kinase antibodyAnti-Mok Protein Kinase antibodyAnti-Renal Tumor Antigen 1 antibodyAnti-Rage-1 antibodyAnti-MOK antibodyAnti-RAGE antibodyAnti-RAGE1 antibody |
Information sourced from Uniprot.org
![Anti-RAGE-1/MOK nanobody [SAA1290] (STJN000315)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/200928/413110/STJN000315-SDS-PAGE-1__29589.1749232609.jpg?c=1 "Anti-RAGE-1/MOK nanobody [SAA1290] (STJN000315)")
