| Tissue Specificity | Ubiquitous. Detected in retina, ocular ciliary body, skeletal muscle, heart, colon, bone marrow, cerebellum, small intestine, fetal brain, fetal liver, kidney, spinal cord, lung, placenta and prostate. |
| Function | Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. |
| Protein Name | Methionine-R-Sulfoxide Reductase B2 - MitochondrialMsrb2 |
| Database Links | Reactome: R-HSA-5676934 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Methionine-R-Sulfoxide Reductase B2 - Mitochondrial antibodyAnti-Msrb2 antibodyAnti-MSRB2 antibodyAnti-CBS-1 antibodyAnti-MSRB antibodyAnti-CGI-131 antibody |
Information sourced from Uniprot.org
