Anti-MTX1 antibody (186-435) (STJ110221)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MTX1 (186-435) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MTX1 |
| Gene ID | 4580 |
| Uniprot ID | MTX1_HUMAN |
| Immunogen Region | 186-435 |
| Immunogen Sequence | LKVHKISNPWQSPSGTLPAL RTSHGEVISVPHKIITHLRK EVHTFWIDTKNYVEVTRKWY AEAMPFPLNFFLPGRMQRQY MERLQLLTGEHRPEDEEELE KELYREARECLTLLSQRLGS QKFFFGDAPASLDAFVFSYL ALLLQAKLPSGKLQVHLRGL HNLCAYCTHILSLYFPWDGA EVPPQRQTPAGPETEEEPYR RRNQILSVLAGLAAMVGYAL LSGIVSIQRATPARAPGTR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 186-435 of human MTX1 (NP_942584.2). |
Additional Info
| Post Translational Modifications | Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30. |
| Function | Involved in transport of proteins into the mitochondrion. Essential for embryonic development. |
| Protein Name | Metaxin-1Mitochondrial Outer Membrane Import Complex Protein 1 |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-8949613Reactome: R-HSA-9013404 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinMitochondrion Outer Membrane |
| Alternative Antibody Names | Anti-Metaxin-1 antibodyAnti-Mitochondrial Outer Membrane Import Complex Protein 1 antibodyAnti-MTX1 antibodyAnti-MTX antibodyAnti-MTXN antibody |
Information sourced from Uniprot.org