Anti-Phospho-CCNB1-Ser126 antibody (91-140 aa) (STJ90239)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human Cyclin B1 around the phosphorylation site of Ser126 at the amino acid range 91-140
General Information
| Short Description | Rabbit polyclonal anti-Phospho-G2/mitotic-specific cyclin-B1-Ser126 (91-140 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCNB1 |
| Gene ID | 891 |
| Uniprot ID | CCNB1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human Cyclin B1 around the phosphorylation site of Ser126 at the amino acid range 91-140 |
| Immunogen Region | 91-140 aa |
| Specificity | Phospho-Cyclin B1 (S126) Polyclonal Antibody detects endogenous levels of Cyclin B1 protein only when phosphorylated at S126. |
Additional Info
| Function | Essential for the control of the cell cycle at the G2/M (mitosis) transition. |
| Protein Name | G2/Mitotic-Specific Cyclin-B1 |
| Database Links | Reactome: R-HSA-113507Reactome: R-HSA-156711Reactome: R-HSA-162658Reactome: R-HSA-174048Reactome: R-HSA-176408Reactome: R-HSA-176412Reactome: R-HSA-176417Reactome: R-HSA-2299718Reactome: R-HSA-2465910Reactome: R-HSA-2500257Reactome: R-HSA-2514853Reactome: R-HSA-2565942Reactome: R-HSA-2980767Reactome: R-HSA-2995383Reactome: R-HSA-3301854Reactome: R-HSA-4419969Reactome: R-HSA-6804114Reactome: R-HSA-68875Reactome: R-HSA-69273Reactome: R-HSA-69478Reactome: R-HSA-75035Reactome: R-HSA-8852276Reactome: R-HSA-8878166Reactome: R-HSA-9725371Reactome: R-HSA-9825892 |
| Cellular Localisation | CytoplasmNucleusCytoskeletonMicrotubule Organizing CenterCentrosome |
| Alternative Antibody Names | Anti-G2/Mitotic-Specific Cyclin-B1 antibodyAnti-CCNB1 antibodyAnti-CCNB antibody |
Information sourced from Uniprot.org