| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | INSR IGF1R |
| Gene ID: | 3643 3480 |
| Uniprot ID: | INSR_HUMAN IGF1R_HUMAN |
| Specificity: | A synthetic phosphorylated peptide around Y1151 of human IGF1RINSR (NP_001073285.1). |
| Immunogen Sequence: | DYYRK |
| Tissue Specificity | P06213 - Isoform Long and isoform Short are predominantly expressed in tissue targets of insulin metabolic effects: liver, adipose tissue and skeletal muscle but are also expressed in the peripheral nerve, kidney, pulmonary alveoli, pancreatic acini, placenta vascular endothelium, fibroblasts, monocytes, granulocytes, erythrocytes and skin. Isoform Short is preferentially expressed in fetal cells such as fetal fibroblasts, muscle, liver and kidney. Found as a hybrid receptor with IGF1R in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Overexpressed in several tumors, including breast, colon, lung, ovary, and thyroid carcinomas. P08069 - Found as a hybrid receptor with INSR in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Expressed in a variety of tissues. Overexpressed in tumors, including melanomas, cancers of the colon, pancreas prostate and kidney. |
| Alternative Antibody Names | Anti-Insulin Receptor antibody Anti-Ir antibody Anti-Cd Antigen Cd220 Cleaved Into - Insulin Receptor Subunit Alpha - Insulin Receptor Subunit Beta antibody Anti-INSR antibody Anti-Insulin-Like Growth Factor 1 Receptor antibody Anti-Insulin-Like Growth Factor I Receptor antibody Anti-Igf-I Receptor antibody Anti-Cd Antigen Cd221 Cleaved Into - Insulin-Like Growth Factor 1 Receptor Alpha Chain - Insulin-Like Growth Factor 1 Receptor Beta Chain antibody Anti-IGF1R antibody |
Information sourced from Uniprot.org