Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-1 is suitable for use in Western Blot and ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | PLCB1 |
Gene ID: | 23236 |
Uniprot ID: | PLCB1_HUMAN |
Specificity: | PLCB1 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from part of the human protein |
Function | Catalyzes the hydrolysis of 1-phosphatidylinositol 4,5-bisphosphate into diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) and mediates intracellular signaling downstream of G protein-coupled receptors. Regulates the function of the endothelial barrier. |
Protein Name | 1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-1 Plc-154 Phosphoinositide Phospholipase C-Beta-1 Phospholipase C-I Plc-I Phospholipase C-Beta-1 Plc-Beta-1 |
Database Links | Reactome: R-HSA-112043 Reactome: R-HSA-1855204 Reactome: R-HSA-399997 Reactome: R-HSA-4086398 Reactome: R-HSA-416476 Reactome: R-HSA-418217 Reactome: R-HSA-434316 Reactome: R-HSA-500657 |
Cellular Localisation | Nucleus Membrane Cytoplasm Colocalizes With The Adrenergic Receptors Adren1a And Adren1b At The Nuclear Membrane Of Cardiac Myocytes |
Alternative Antibody Names | Anti-1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-1 antibody Anti-Plc-154 antibody Anti-Phosphoinositide Phospholipase C-Beta-1 antibody Anti-Phospholipase C-I antibody Anti-Plc-I antibody Anti-Phospholipase C-Beta-1 antibody Anti-Plc-Beta-1 antibody Anti-PLCB1 antibody Anti-KIAA0581 antibody |
Information sourced from Uniprot.org