Anti-PLEKHF2 antibody (STJA0004785)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFusion protein of human PLEKHF2
General Information
| Short Description | Rabbit polyclonal anti-Pleckstrin Homology Domain-Containing Family F Member 2 for use in WB, IHC and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1.62 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | WB 1:1000-1:5000, IHC 1:100-1:300 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | PLEKHF2 |
| Gene ID | 79666 |
| Uniprot ID | PKHF2_HUMAN |
| Immunogen | Fusion protein of human PLEKHF2 |
Additional Info
| Tissue Specificity | Expressed in placenta, ovary and small intestine, as well as in heart and pancreas. Also expressed in peripheral blood mononuclear cells and dendritic cells. |
| Function | May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis. |
| Protein Name | Pleckstrin Homology Domain-Containing Family F Member 2Ph Domain-Containing Family F Member 2Endoplasmic Reticulum-Associated Apoptosis-Involved Protein Containing Ph And Fyve DomainsEapfPh And Fyve Domain-Containing Protein 2Phafin-2Phafin2Zinc Finger Fyve Domain-Containing Protein 18 |
| Database Links | |
| Cellular Localisation | Early Endosome MembranePeripheral Membrane ProteinEndoplasmic ReticulumColocalizes With Eea1 And Rab5 At Endosomal Membrane Fusion Hot SpotsMay Translocate To The Endoplasmic Reticulum In The Early Phase Of Apoptosis |
| Alternative Antibody Names | Anti-Pleckstrin Homology Domain-Containing Family F Member 2 antibodyAnti-Ph Domain-Containing Family F Member 2 antibodyAnti-Endoplasmic Reticulum-Associated Apoptosis-Involved Protein Containing Ph And Fyve Domains antibodyAnti-Eapf antibodyAnti-Ph And Fyve Domain-Containing Protein 2 antibodyAnti-Phafin-2 antibodyAnti-Phafin2 antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 18 antibodyAnti-PLEKHF2 antibodyAnti-ZFYVE18 antibody |
Information sourced from Uniprot.org