Western blot analysis of various lysates using PNKD Rabbit pAb (STJ117854) at 1:1000 dilution. <br/>Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. <br/>Lysates/proteins: 25 Mu g per lane. <br/>Blocking buffer: 3% nonfat dry milk in TBST. <br/>Detection: ECL Basic Kit <br/>Exposure time: 90s.

Anti-PNKD antibody (1-270) (STJ117854)

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STJ117854
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Applications:WB/IF/ICC/ELISA
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:PNKD
Gene ID:25953
Uniprot ID:PNKD_HUMAN
Immunogen Region:1-270
Immunogen Sequence:MAAVVAATALKGRGARNARV LRGILAGATANKASHNRTRA LQSHSSPEGKEEPEPLSPEL EYIPRKRGKNPMKAVGLAWY SLYTRTWLGYLFYRQQLRRA RNRYPKGHSKTQPRLFNGVK VLPIPVLSDNYSYLIIDTQA QLAVAVDPSDPRAVQASIEK EGVTLVAILCTHKHWDHSGG NRDLSRRHRDCRVYGSPQDG IPYLTHPLCHQDVVSVGRLQ IRALATPGHTQGHLVYLLD
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human PNKD (NP_056303.3).
Tissue Specificity Isoform 1 is only expressed in the brain. Isoform 2 is ubiquitously detected with highest expression in skeletal muscle and detected in myocardial myofibrils.
Post Translational Modifications Undergoes cleavage at the N-terminus.
Function Probable thioesterase that may play a role in cellular detoxification processes.it likely acts on a yet-unknown alpha-hydroxythioester substrate (Probable). In vitro, it is able to catalyze the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid at very low rate, though this reaction is not physiologically relevant in vivo.
Protein Name Probable Thioesterase Pnkd
Myofibrillogenesis Regulator 1
Mr-1
Paroxysmal Nonkinesiogenic Dyskinesia Protein
Trans-Activated By Hepatitis C Virus Core Protein 2
Database Links Reactome: R-HSA-9864848 Q8N490-2
Cellular Localisation Isoform 1: Cell Membrane
Peripheral Membrane Protein
Mitochondrion
Isoform 2: Cytoplasm
Isoform 3: Mitochondrion
Golgi Apparatus
Endoplasmic Reticulum
Alternative Antibody Names Anti-Probable Thioesterase Pnkd antibody
Anti-Myofibrillogenesis Regulator 1 antibody
Anti-Mr-1 antibody
Anti-Paroxysmal Nonkinesiogenic Dyskinesia Protein antibody
Anti-Trans-Activated By Hepatitis C Virus Core Protein 2 antibody
Anti-PNKD antibody
Anti-KIAA1184 antibody
Anti-MR1 antibody
Anti-TAHCCP2 antibody
Anti-FKSG19 antibody
Anti-UNQ2491 antibody
Anti-PRO5778 antibody

Information sourced from Uniprot.org

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