| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-POLL/POLkappa (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.5-1µg/mlELISA-antibody detection limit dilution 1:32000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
POLL |
| Gene ID: |
27343 |
| Uniprot ID: |
DPOLL_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_037406.1 |
| Specificity: |
It has been brought to our attention that this product may crossreact with Pol beta (NP_002681) , an evolutionarilly related polymerase with a predicted size of 39 kDa. The overall % of identity is not very high (about 32% in the core) but considerin |
| Immunogen Sequence: |
LGLPYREPAERDW |
| Function | DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. |
| Protein Name | Dna Polymerase LambdaPol LambdaDna Polymerase Beta-2Pol Beta2Dna Polymerase Kappa |
| Database Links | Reactome: R-HSA-5693571 |
| Cellular Localisation | NucleusChromosomeAccumulates At Sites Of Dna Damage |
| Alternative Antibody Names | Anti-Dna Polymerase Lambda antibodyAnti-Pol Lambda antibodyAnti-Dna Polymerase Beta-2 antibodyAnti-Pol Beta2 antibodyAnti-Dna Polymerase Kappa antibodyAnti-POLL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
