Anti-PRPF4 antibody (1-260) (STJ27846)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PRPF4 (1-260) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PRPF4 |
| Gene ID | 9128 |
| Uniprot ID | PRP4_HUMAN |
| Immunogen Region | 1-260 |
| Immunogen Sequence | MASSRASSTQATKTKAPDDL VAPVVKKPHIYYGSLEEKER ERLAKGESGILGKDGLKAGI EAGNINITSGEVFEIEEHIS ERQAEVLAEFERRKRARQIN VSTDDSEVKACLRALGEPIT LFGEGPAERRERLRNILSVV GTDALKKTKKDDEKSKKSKE EYQQTWYHEGPNSLKVARLW IANYSLPRAMKRLEEARLHK EIPETTRTSQMQELHKSLRS LNNFCSQIGDDRPISYCHF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PRPF4 (NP_004688.2). |
Additional Info
| Function | Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). |
| Protein Name | U4/U6 Small Nuclear Ribonucleoprotein Prp4Prp4 HomologHprp4U4/U6 Snrnp 60 Kda ProteinWd Splicing Factor Prp4 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | NucleusNucleus Speckle |
| Alternative Antibody Names | Anti-U4/U6 Small Nuclear Ribonucleoprotein Prp4 antibodyAnti-Prp4 Homolog antibodyAnti-Hprp4 antibodyAnti-U4/U6 Snrnp 60 Kda Protein antibodyAnti-Wd Splicing Factor Prp4 antibodyAnti-PRPF4 antibodyAnti-PRP4 antibody |
Information sourced from Uniprot.org