Anti-PTGER4 antibody (321-370 aa) (STJ92935)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PE2R4 at the amino acid range 321-370
General Information
| Short Description | Rabbit polyclonal anti-Prostaglandin E2 receptor EP4 subtype (321-370 aa) for use in WB, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PTGER4 |
| Gene ID | 5734 |
| Uniprot ID | PE2R4_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human PE2R4 at the amino acid range 321-370 |
| Immunogen Region | 321-370 aa |
| Specificity | EP4 Polyclonal Antibody detects endogenous levels of EP4 protein. |
Additional Info
| Post Translational Modifications | Phosphorylation mediates agonist-mediated desensitization by promoting cytoplasmic retention. |
| Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. |
| Protein Name | Prostaglandin E2 Receptor Ep4 SubtypePge Receptor Ep4 SubtypePge2 Receptor Ep4 SubtypeProstanoid Ep4 Receptor |
| Database Links | Reactome: R-HSA-391908Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Prostaglandin E2 Receptor Ep4 Subtype antibodyAnti-Pge Receptor Ep4 Subtype antibodyAnti-Pge2 Receptor Ep4 Subtype antibodyAnti-Prostanoid Ep4 Receptor antibodyAnti-PTGER4 antibodyAnti-PTGER2 antibody |
Information sourced from Uniprot.org