Anti-RERE antibody (1-220) (STJ117450)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RERE (1-220) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RERE |
| Gene ID | 473 |
| Uniprot ID | RERE_HUMAN |
| Immunogen Region | 1-220 |
| Immunogen Sequence | MTADKDKDKDKEKDRDRDRD REREKRDKARESENSRPRRS CTLEGGAKNYAESDHSEDED NDNNSATAEESTKKNKKKPP KKKSRYERTDTGEITSYITE DDVVYRPGDCVYIESRRPNT PYFICSIQDFKLVHNSQACC RSPTPALCDPPACSLPVASQ PPQHLSEAGRGPVGSKRDHL LMNVKWYYRQSEVPDSVYQH LVQDRHNENDSGRELVITDP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human RERE (NP_036234.3). |
Additional Info
| Tissue Specificity | Widely expressed. Expressed in tumor cell lines. |
| Function | Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death. |
| Protein Name | Arginine-Glutamic Acid Dipeptide Repeats ProteinAtrophin-1-Like ProteinAtrophin-1-Related Protein |
| Database Links | |
| Cellular Localisation | NucleusLocalized In Nuclear Bodies Of Variables SizeColocalized With Pml And Bax In Nuclear Pods |
| Alternative Antibody Names | Anti-Arginine-Glutamic Acid Dipeptide Repeats Protein antibodyAnti-Atrophin-1-Like Protein antibodyAnti-Atrophin-1-Related Protein antibodyAnti-RERE antibodyAnti-ARG antibodyAnti-ARP antibodyAnti-ATN1L antibodyAnti-KIAA0458 antibody |
Information sourced from Uniprot.org