Anti-ROMO1 antibody (1-79) (STJ11105454)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Reactive Oxygen Species Modulator 1 (1-79) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ROMO1 |
| Gene ID | 140823 |
| Uniprot ID | ROMO1_HUMAN |
| Immunogen Region | 1-79 |
| Immunogen Sequence | MPVAVGPYGQSQPSCFDRVK MGFVMGCAVGMAAGALFGTF SCLRIGMRGRELMGGIGKTM MQSGGTFGTFMAIGMGIRC |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-79 of human ROMO1 (NP_542786.1). |
Additional Info
| Tissue Specificity | Up-regulated in a number of cancer cell lines when compared to a normal lung fibroblast cell line. Highly expressed in brain tumors. |
| Function | Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation. Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage. |
| Protein Name | Reactive Oxygen Species Modulator 1Ros Modulator 1Epididymis Tissue Protein Li 175GlyrichinMitochondrial Targeting Gxxxg Motif ProteinMtgmProtein Mgr2 Homolog |
| Database Links | |
| Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Reactive Oxygen Species Modulator 1 antibodyAnti-Ros Modulator 1 antibodyAnti-Epididymis Tissue Protein Li 175 antibodyAnti-Glyrichin antibodyAnti-Mitochondrial Targeting Gxxxg Motif Protein antibodyAnti-Mtgm antibodyAnti-Protein Mgr2 Homolog antibodyAnti-ROMO1 antibodyAnti-C20orf52 antibody |
Information sourced from Uniprot.org