| Tissue Specificity | Retina. Expressed throughout the horizontal cells or more specifically at the terminals. |
| Function | Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals. The transport is equally dependent on the chemical and electrical components of the proton gradient. May also transport beta-alanine. Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake. |
| Protein Name | Vesicular Inhibitory Amino Acid TransporterGaba And Glycine TransporterSolute Carrier Family 32 Member 1Vesicular Gaba TransporterHviaat |
| Database Links | Reactome: R-HSA-425393Reactome: R-HSA-888590 |
| Cellular Localisation | Cytoplasmic Vesicle MembraneMulti-Pass Membrane ProteinPresynapsePresents In Glycine-Gaba- Or Gaba- And Glycine-Containing Boutons |
| Alternative Antibody Names | Anti-Vesicular Inhibitory Amino Acid Transporter antibodyAnti-Gaba And Glycine Transporter antibodyAnti-Solute Carrier Family 32 Member 1 antibodyAnti-Vesicular Gaba Transporter antibodyAnti-Hviaat antibodyAnti-SLC32A1 antibodyAnti-VGAT antibodyAnti-VIAAT antibody |
Information sourced from Uniprot.org
