| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLK (1-230) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLK |
| Gene ID: |
9748 |
| Uniprot ID: |
SLK_HUMAN |
| Immunogen Region: |
1-230 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human SLK (NP_055535.2). |
| Immunogen Sequence: |
MSFFNFRKIFKLGSEKKKKQ YEHVKRDLNPEDFWEIIGEL GDGAFGKVYKAQNKETSVLA AAKVIDTKSEEELEDYMVEI DILASCDHPNIVKLLDAFYY ENNLWILIEFCAGGAVDAVM LELERPLTESQIQVVCKQTL DALNYLHDNKIIHRDLKAGN ILFTLDGDIKLADFGVSAKN TRTIQRRDSFIGTPYWMAPE VVMCETSKDRPYDYKADVWS LGITLIEMAE |
| Tissue Specificity | Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle. |
| Post Translational Modifications | Proteolytically cleaved by caspase-3. Autophosphorylated. |
| Function | Mediates apoptosis and actin stress fiber dissolution. |
| Protein Name | Ste20-Like Serine/Threonine-Protein KinaseSte20-Like KinaseHslkCtcl Tumor Antigen Se20-9Ste20-Related Serine/Threonine-Protein KinaseSte20-Related KinaseSerine/Threonine-Protein Kinase 2 |
| Database Links | Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ste20-Like Serine/Threonine-Protein Kinase antibodyAnti-Ste20-Like Kinase antibodyAnti-Hslk antibodyAnti-Ctcl Tumor Antigen Se20-9 antibodyAnti-Ste20-Related Serine/Threonine-Protein Kinase antibodyAnti-Ste20-Related Kinase antibodyAnti-Serine/Threonine-Protein Kinase 2 antibodyAnti-SLK antibodyAnti-KIAA0204 antibodyAnti-STK2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
