• Western blot analysis of extracts of various cell lines, using SNRNP200 antibody (STJ27857) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-SNRNP200 antibody (1947-2136) (STJ27857)

SKU:
STJ27857

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SNRNP200 (1947-2136) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SNRNP200
Gene ID: 23020
Uniprot ID: U520_HUMAN
Immunogen Region: 1947-2136
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1947-2136 of human SNRNP200 (NP_054733.2).
Immunogen Sequence: QMVTQAMWSKDSYLKQLPHF TSEHIKRCTDKGVESVFDIM EMEDEERNALLQLTDSQIAD VARFCNRYPNIELSYEVVDK DSIRSGGPVVVLVQLEREEE VTGPVIAPLFPQKREEGWWV VIGDAKSNSLISIKRLTLQQ KAKVKLDFVAPATGAHNYTL YFMSDAYMGCDQEYKFSVDV KEAETDSDSD
Tissue Specificity Widely expressed.
Function Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome. Plays a role in pre-mRNA splicing as a core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). Involved in spliceosome assembly, activation and disassembly. Mediates changes in the dynamic network of RNA-RNA interactions in the spliceosome.
Protein Name U5 Small Nuclear Ribonucleoprotein 200 Kda Helicase
Activating Signal Cointegrator 1 Complex Subunit 3-Like 1
Brr2 Homolog
U5 Snrnp-Specific 200 Kda Protein
U5-200kd
Database Links Reactome: R-HSA-72163
Reactome: R-HSA-72165
Cellular Localisation Nucleus
Alternative Antibody Names Anti-U5 Small Nuclear Ribonucleoprotein 200 Kda Helicase antibody
Anti-Activating Signal Cointegrator 1 Complex Subunit 3-Like 1 antibody
Anti-Brr2 Homolog antibody
Anti-U5 Snrnp-Specific 200 Kda Protein antibody
Anti-U5-200kd antibody
Anti-SNRNP200 antibody
Anti-ASCC3L1 antibody
Anti-BRR2 antibody
Anti-HELIC2 antibody
Anti-KIAA0788 antibody

Information sourced from Uniprot.org

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