Anti-ST2 antibody [10206] (STJ400215)

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STJ400215

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Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-ST2 is suitable for use in ELISA research applications.
Clonality: Monoclonal
Clone ID: 10206
Conjugation: Unconjugated
Isotype: IgG1
Formulation: 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
Purification: Greater than 95% purity
Concentration: 5.0 mg/ml (+/-10 %)
Storage Instruction: 12 months from manufacturing at 2–8°C. Temperature analysis:-70 °C, 21 days Not Determined (N/D)-20 °C, 14 days OK +4 °C, 14 days OK +35 °C, 14 days OK +45 °C, 7 days OK. Shelf life stability testing at 2–8 °C in the product buffer.
Association Rate Constant: 2.1 x 106 1/Ms
Determination Method: SPR analysis (ProteOn XPR36)
Immunoreactivity: 80–120 % compared to the reference sample in an FIA test
Gene Symbol: SULT2A1
Gene ID: 6822
Uniprot ID: ST2A1_HUMAN
Immunogen: Human soluble ST2
Tissue Specificity Liver, adrenal and at lower level in the kidney. Is present in human fetus in higher level in the adrenal than the liver and the kidney.
Post Translational Modifications The N-terminus is blocked.
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. Mediates the sulfation of a wide range of steroids and sterols, including pregnenolone, androsterone, DHEA, bile acids, cholesterol and as well many xenobiotics that contain alcohol and phenol functional groups. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Plays an important role in maintening steroid and lipid homeostasis. Plays a key role in bile acid metabolism. In addition, catalyzes the metabolic activation of potent carcinogenic polycyclic arylmethanols.
Protein Name Sulfotransferase 2a1
St2a1
Bile Salt Sulfotransferase
Dehydroepiandrosterone Sulfotransferase
Dhea-St
Dhea-St8
Hydroxysteroid Sulfotransferase
Hst
St2
Sult2a3
Database Links Reactome: R-HSA-156584
Reactome: R-HSA-1989781
Reactome: R-HSA-9753281
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Sulfotransferase 2a1 antibody
Anti-St2a1 antibody
Anti-Bile Salt Sulfotransferase antibody
Anti-Dehydroepiandrosterone Sulfotransferase antibody
Anti-Dhea-St antibody
Anti-Dhea-St8 antibody
Anti-Hydroxysteroid Sulfotransferase antibody
Anti-Hst antibody
Anti-St2 antibody
Anti-Sult2a3 antibody
Anti-SULT2A1 antibody
Anti-HST antibody
Anti-STD antibody

Information sourced from Uniprot.org

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