Anti-Stat5 antibody (666-715 aa) (STJ95818)

SKU:
STJ95818
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Signal transducer and activator of transcription 5A and Signal transducer and activator of transcription 5B (666-715 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recomme
Applications:WB/IHC/IF/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:STAT5A
STAT5B
Gene ID:6776
6777
Uniprot ID:STA5A_HUMAN
STA5B_HUMAN
Immunogen:The antiserum was produced against synthesized peptide derived from the human STAT5A at the amino acid range 666-715
Immunogen Region:666-715 aa
Specificity:Stat5 Polyclonal Antibody detects endogenous levels of Stat5 protein.
Function Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.
Protein Name Signal Transducer And Activator Of Transcription 5a
Database Links Reactome: R-HSA-1170546
Reactome: R-HSA-1251985
Reactome: R-HSA-1266695
Reactome: R-HSA-1433557
Reactome: R-HSA-1839117
Reactome: R-HSA-186763
Reactome: R-HSA-2586552
Reactome: R-HSA-512988
Reactome: R-HSA-8854691
Reactome: R-HSA-8983432
Reactome: R-HSA-8985947
Reactome: R-HSA-9020558
Reactome: R-HSA-9020958
Reactome: R-HSA-9027283
Reactome: R-HSA-9645135
Reactome: R-HSA-9670439
Reactome: R-HSA-982772
Cellular Localisation Cytoplasm
Nucleus
Translocated Into The Nucleus In Response To Phosphorylation
Alternative Antibody Names Anti-Signal Transducer And Activator Of Transcription 5a antibody
Anti-STAT5A antibody
Anti-STAT5 antibody

Information sourced from Uniprot.org