| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Tax1-binding protein 3 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TAX1BP3 |
| Gene ID: | 30851 |
| Uniprot ID: | TX1B3_HUMAN |
| Specificity: | This antibody detects endogenous levels of TAX1BP3 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human TAX1BP3 |
| Tissue Specificity | Ubiquitous. Detected in brain, heart, kidney, lung, small intestine and skeletal muscle. Detected in various cell lines including HeLa. Weakly expressed in peripheral blood leukocytes. |
| Function | May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6. |
| Protein Name | Tax1-Binding Protein 3 Glutaminase-Interacting Protein 3 Tax Interaction Protein 1 Tip-1 Tax-Interacting Protein 1 |
| Database Links | Reactome: R-HSA-5666185 |
| Cellular Localisation | Cytoplasm Nucleus Cell Membrane Peripheral Membrane Protein Cytoplasmic Side Recruited To The Cell Membrane By Interaction With Membrane Proteins |
| Alternative Antibody Names | Anti-Tax1-Binding Protein 3 antibody Anti-Glutaminase-Interacting Protein 3 antibody Anti-Tax Interaction Protein 1 antibody Anti-Tip-1 antibody Anti-Tax-Interacting Protein 1 antibody Anti-TAX1BP3 antibody Anti-TIP1 antibody |
Information sourced from Uniprot.org