| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TBXA2R (229-343) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TBXA2R |
| Gene ID: |
6915 |
| Uniprot ID: |
TA2R_HUMAN |
| Immunogen Region: |
229-343 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 229-343 of human TBXA2R (NP_001051.1). |
| Immunogen Sequence: |
QEAAQQRPRDSEVEMMAQLL GIMVVASVCWLPLLVFIAQT VLRNPPAMSPAGQLSRTTEK ELLIYLRVATWNQILDPWVY ILFRRAVLRRLQPRLSTRPR SLSLQPQLTQRSGLQ |
| Function | Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1: Activates adenylyl cyclase. Isoform 2: Inhibits adenylyl cyclase. |
| Protein Name | Thromboxane A2 ReceptorTxa2-RProstanoid Tp Receptor |
| Database Links | Reactome: R-HSA-391908Reactome: R-HSA-416476Reactome: R-HSA-416482Reactome: R-HSA-428930 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Thromboxane A2 Receptor antibodyAnti-Txa2-R antibodyAnti-Prostanoid Tp Receptor antibodyAnti-TBXA2R antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
