Anti-TRH antibody (25-230) (STJ110620)

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STJ110620
£110.50 - £505.50
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Applications:WB/IF/ICC/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
IF/ICC:1:100-1:500
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:TRH
Gene ID:7200
Uniprot ID:TRH_HUMAN
Immunogen Region:25-230
Immunogen Sequence:QPEAAQQEAVTAAEHPGLDD FLRQVERLLFLRENIQRLQG DQGEHSASQIFQSDWLSKRQ HPGKREEEEEEGVEEEEEEE GGAVGPHKRQHPGRREDEAS WSVDVTQHKRQHPGRRSPWL AYAVPKRQHPGRRLADPKAQ RSWEEEEEEEEREEDLMPEK RQHPGKRALGGPCGPQGAYG QAGLLLGLLDDLSRSQGAEE KRQHPG
Specificity:A synthetic peptide corresponding to a sequence within amino acids 25-230 of human TRH (NP_009048.1).
Tissue Specificity Hypothalamus. Expressed in the hair follicle epithelium (at protein level).
Function As a component of the hypothalamic-pituitary-thyroid axis, it controls the secretion of thyroid-stimulating hormone (TSH) and is involved in thyroid hormone synthesis regulation. It also operates as modulator of hair growth. It promotes hair-shaft elongation, prolongs the hair cycle growth phase (anagen) and antagonizes its termination (catagen) by TGFB2. It stimulates proliferation and inhibits apoptosis of hair matrix keratinocytes.
Protein Name Pro-Thyrotropin-Releasing Hormone
Pro-Trh
Prothyroliberin Cleaved Into - Thyrotropin-Releasing Hormone
Trh
Protirelin
Tsh-Releasing Factor
Thyroliberin
Thyrotropin-Releasing Factor
Trf
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Cellular Localisation Secreted
Alternative Antibody Names Anti-Pro-Thyrotropin-Releasing Hormone antibody
Anti-Pro-Trh antibody
Anti-Prothyroliberin Cleaved Into - Thyrotropin-Releasing Hormone antibody
Anti-Trh antibody
Anti-Protirelin antibody
Anti-Tsh-Releasing Factor antibody
Anti-Thyroliberin antibody
Anti-Thyrotropin-Releasing Factor antibody
Anti-Trf antibody
Anti-TRH antibody

Information sourced from Uniprot.org