Anti-Trypsinogen-2 antibody [8603] (STJ400189)

SKU:
STJ400189

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Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Trypsinogen-2 is suitable for use in ELISA research applications.
Clonality: Monoclonal
Clone ID: 8603
Conjugation: Unconjugated
Isotype: IgG2b
Formulation: 37 mM citrate, 125 mM phosphate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
Purification: Purity accurate to greater than or equal to 95%
Concentration: 5.0 mg/ml (+/-10 %)
Storage Instruction: 24 months from manufacturing at 2°C. Temperature analysis:-70 °C, 21 days N/D-20 °C, 21 days OK +4 °C, 21 days OK +30 °C, 21 OK +35 °C, 21 days OK +45 °C, 7 days OK. Shelf life stability testing at 2–8 °C in the product buffer.
Association Rate Constant: 8.9 x 105 1/Ms
Determination Method: SPR analysis (ProteOn XPR36)
Immunoreactivity: 80–120 % compared to the reference sample in an FIA test
Immunogen: human trypsinogen-2
Background Trypsinogen is the precursor form of the pancreatic enzyme trypsin. It is found in pancreatic juice, along with amylase, lipase, and chymotrypsinogen. It is activated by enteropeptidase, which is found in the intestinal mucosa, to form trypsin. Once activated, the trypsin can activate more trypsinogen into trypsin. Trypsin cleaves peptide bond on carboxyl side of basic amino acids. High serum trypsinogen levels are seen in acute pancreatitis, and cystic fibrosis. Determination of urine trypsinogen-2 is also a useful test to detect acute pancreatitis and to evaluate disease severity.

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance