Confocal imaging of U-2 OS cells using PBR/TSPO Rabbit monoclonal antibody (STJ11102178, dilution 1:100) (Red). The cells were counterstained with Alpha-Tubulin Mouse monoclonal antibody (dilution 1:400) (Green). DAPI was used for nuclear staining (blue). Objective: 100x.

Anti-TSPO antibody (70-169) [S8MR] (STJ11102178)

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STJ11102178
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Applications:WB/IHC-P/IF/ICC/ELISA
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :S8MR
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:1000-1:6000
IHC-P:1:200-1:2000
IF/ICC:1:100-1:400
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:TSPO
Gene ID:706
Uniprot ID:TSPO_HUMAN
Immunogen Region:70-169
Immunogen Sequence:ELGGFTEKAVVPLGLYTGQL ALNWAWPPIFFGARQMGWAL VDLLLVSGAAAATTVAWYQV SPLAARLLYPYLAWLAFTTT LNYCVWRDNHGWRGGRRLPE
Specificity:A synthetic peptide corresponding to a sequence within amino acids 70-169 of human PBR/TSPO (P30536).
Tissue Specificity Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids.
Function Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor.can also bind isoquinoline carboxamides.
Protein Name Translocator Protein
Mitochondrial Benzodiazepine Receptor
Pkbs
Peripheral-Type Benzodiazepine Receptor
Pbr
Database Links Reactome: R-HSA-196108
Cellular Localisation Mitochondrion Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Translocator Protein antibody
Anti-Mitochondrial Benzodiazepine Receptor antibody
Anti-Pkbs antibody
Anti-Peripheral-Type Benzodiazepine Receptor antibody
Anti-Pbr antibody
Anti-TSPO antibody
Anti-BZRP antibody
Anti-MBR antibody

Information sourced from Uniprot.org

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