Anti-XDH antibody (202-293) [S0MR] (STJ11102410)

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STJ11102410
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Applications:WB/IHC-P/IF/ICC/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :S0MR
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:1000-1:2000
IHC-P:1:200-1:2000
IF/ICC:1:200-1:400
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:XDH
Gene ID:7498
Uniprot ID:XDH_HUMAN
Immunogen Region:202-293
Immunogen Sequence:TPLDPTQEPIFPPELLRLKD TPRKQLRFEGERVTWIQAST LKELLDLKAQHPDAKLVVGN TEIGIEMKFKNMLFPMIVCP AWIPELNSVEHG
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 202-293 of human Xanthine Oxidase (XDH) (P47989).
Tissue Specificity Detected in milk (at protein level).
Post Translational Modifications Subject to partial proteolysis.this alters the enzyme from the dehydrogenase form (D) to the oxidase form (O). Contains sulfhydryl groups that are easily oxidized (in vitro).this alters the enzyme from the dehydrogenase form (D) to the oxidase form (O).
Function Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).
Protein Name Xanthine Dehydrogenase/Oxidase Includes - Xanthine Dehydrogenase
Xd - Xanthine Oxidase
Xo
Xanthine Oxidoreductase
Xor
Database Links Reactome: R-HSA-74259
Reactome: R-HSA-8851680
Reactome: R-HSA-9748787
Cellular Localisation Cytoplasm
Peroxisome
Secreted
Alternative Antibody Names Anti-Xanthine Dehydrogenase/Oxidase Includes - Xanthine Dehydrogenase antibody
Anti-Xd - Xanthine Oxidase antibody
Anti-Xo antibody
Anti-Xanthine Oxidoreductase antibody
Anti-Xor antibody
Anti-XDH antibody
Anti-XDHA antibody

Information sourced from Uniprot.org