• Human CCL17 (C-C motif chemokine 17) CLIA Kit (STJC0000026)

Human CCL17 (C-C motif chemokine 17) CLIA Kit (STJC0000026)

SKU:
STJC0000026

£238.50 - £477.50
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Applications: CLIA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Sensitivity: 7.5pg/mL
Detection Limit: 12.5~800pg/mL
Short Description: This human CCL17 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
Storage Instruction: If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time: 3.5h
Detection: Chemiluminescence
Gene Symbol: CCL17
Gene ID: 6361
Uniprot ID: CCL17_HUMAN
Specificity: This kit recognizes Human TARC in samples. No significant cross-reactivity or interference between Human TARC and analogues was observed.
Sample Type: Serum, plasma and other biological fluids
Tissue Specificity Constitutively expressed in thymus. Detected at lower levels in the lung, colon and small intestine. Expressed in stimulated peripheral blood mononuclear cells, but not in resting cells.
Function Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. May be important for the appropriate adaptation of microglial morphology and synaptic plasticity to acute lipopolysaccharide (LPS)-induced neuroinflammation. Plays a role in wound healing, mainly by inducing fibroblast migration into the wound.
Protein Name C-C Motif Chemokine 17
Cc Chemokine Tarc
Small-Inducible Cytokine A17
Thymus And Activation-Regulated Chemokine
Database Links Reactome: R-HSA-380108
Cellular Localisation Secreted
Alternative CLIA Names C-C Motif Chemokine 17 CLIA kit
Cc Chemokine Tarc CLIA kit
Small-Inducible Cytokine A17 CLIA kit
Thymus And Activation-Regulated Chemokine CLIA kit
CCL17 CLIA kit
SCYA17 CLIA kit
TARC CLIA kit
Specificity This kit recognizes Human TARC in samples. No significant cross-reactivity or interference between Human TARC and analogues was observed.
Reproducibility Both intra-CV and inter-CV are

Information sourced from Uniprot.org


Item Specifications Storage
Micro CLIA Plate (Dismountable) 96T: 8 wells ×12 strips strips -20℃, 6 months
Reference Standard 96T: 2 vials 48T: 1 vial -20℃, 6 months
Concentrated Biotinylated Detection Ab (100×) 96T: 1 vial, 120 μL 60 μL -20℃, 6 months
Concentrated HRP Conjugate (100×) 96T: 1 vial, 120 μL 60 μL -20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent 1 vial, 20 mL 2-8°C, 6 months
Biotinylated Detection Ab Diluent 1 vial, 14 mL 2-8°C, 6 months
HRP Conjugate Diluent 1 vial, 14 mL 2-8°C, 6 months
Concentrated Wash Buffer (25×) 1 vial, 30 mL 2-8°C, 6 months
Substrate Reagent A 1 vial, 5 mL 2-8℃ (Protect from light)
Substrate Reagent B 1 vial, 5 mL 2-8℃ (Protect from light)
Plate Sealer 5 pieces
Manual 1 copy
Certificate of Analysis 1 copy

Sample Type Range (%) Average Recovery (%)
Serum(n=8) 92-105 98
EDTA plasma(n=8) 86-99 92
Cell culture media(n=8) 91-108 99

Intra-assay Precision Intra-assay Precision Intra-assay Precision Inter-assay Precision Inter-assay Precision Inter-assay Precision
Sample 1.00 2.00 3.00 1.00 2.00 3.00
n 20.00 20.00 20.00 20.00 20.00 20.00
Mean (pg/mL) 41.32 106.81 382.44 39.32 109.52 411.93
Standard deviation 3.50 7.88 29.95 3.86 8.62 38.89
CV (%) 8.47 7.38 7.83 9.82 7.87 9.44
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance