| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.59ng/mL |
| Detection Limit: |
1.56-100ng/mL |
| Short Description: |
This PRSS8 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
PRSS8 |
| Gene ID: |
5652 |
| Uniprot ID: |
PRSS8_HUMAN |
| Sample Type: |
serum, plasma, urine or other biological fluids. |
| Tissue Specificity | Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid. |
| Post Translational Modifications | |
| Function | Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G). |
| Protein Name | ProstasinChannel-Activating Protease 1Cap1Serine Protease 8 Cleaved Into - Prostasin Light Chain - Prostasin Heavy Chain |
| Database Links | Reactome: R-HSA-6809371 |
| Cellular Localisation | Prostasin: Cell MembraneSingle-Pass Membrane ProteinProstasin Light Chain: SecretedExtracellular SpaceFound In The Seminal FluidSecreted After Cleavage Of Its C-TerminusProstasin Heavy Chain: Secreted |
| Alternative ELISA Names | Prostasin ELISA kitChannel-Activating Protease 1 ELISA kitCap1 ELISA kitSerine Protease 8 Cleaved Into - Prostasin Light Chain - Prostasin Heavy Chain ELISA kitPRSS8 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
