• Rat CAMK2g (Calcium/Calmodulin Dependent Protein Kinase II Gamma) Sandwich ELISA Kit Ready-To-Use (STJE0014034)

Rat CAMK2g (Calcium/Calmodulin Dependent Protein Kinase II Gamma) Sandwich ELISA Kit Ready-To-Use (STJE0014034)

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STJE0014034

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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.123ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This CAMK2g Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Camk2g
Gene ID: 171140
Uniprot ID: KCC2G_RAT
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Autophosphorylation of Thr-287 following activation by Ca(2+)/calmodulin. Phosphorylation of Thr-287 locks the kinase into an activated state.
Function Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplasmic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In the central nervous system, it is involved in the regulation of neurite formation and arborization. It may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In response to interferon-gamma (IFN-gamma) stimulation, catalyzes phosphorylation of STAT1, stimulating the JAK-STAT signaling pathway.
Protein Name Calcium/Calmodulin-Dependent Protein Kinase Type Ii Subunit Gamma
Cam Kinase Ii Subunit Gamma
Camk-Ii Subunit Gamma
Database Links Reactome: R-RNO-3371571
Reactome: -RNO-399719
Reactome: -RNO-438066
Reactome: -RNO-5578775
Reactome: -RNO-5673000
Reactome: -RNO-5673001
Reactome: -RNO-877300
Reactome: -RNO-936837
Cellular Localisation Sarcoplasmic Reticulum Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Alternative ELISA Names Calcium/Calmodulin-Dependent Protein Kinase Type Ii Subunit Gamma ELISA kit
Cam Kinase Ii Subunit Gamma ELISA kit
Camk-Ii Subunit Gamma ELISA kit
Camk2g ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance