• Rat ERb (Estrogen Receptor Beta) Sandwich ELISA Kit Ready-To-Use (STJE0015067)

Rat ERb (Estrogen Receptor Beta) Sandwich ELISA Kit Ready-To-Use (STJE0015067)

SKU:
STJE0015067

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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.112ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This ERb Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Esr2
Gene ID: 25149
Uniprot ID: ESR2_RAT
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expressed in prostate, ovary, lung, liver, kidney, fat, bone, brain, uterus and testis.
Post Translational Modifications Phosphorylation at Ser-87 and Ser-105 recruits NCOA1.
Function Isoform 1: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform 2: Lacks ligand binding affinity and suppresses ESR1/ER-alpha and ESR2 isoform 1/ER-beta1 mediated transcriptional activation and may act as a dominant negative regulator of estrogen action. Isoform 3: Unable to bind DNA and activate transcription due to the truncation of the DNA binding domain. Isoform 4: Unable to bind DNA and activate transcription due to the truncation of the DNA binding domain.
Protein Name Estrogen Receptor Beta
Er-Beta
Nuclear Receptor Subfamily 3 Group A Member 2
Database Links Reactome: R-RNO-1257604
Reactome: -RNO-383280
Reactome: -RNO-6811558
Reactome: -RNO-8939211
Reactome: -RNO-9009391
Cellular Localisation Nucleus
Alternative ELISA Names Estrogen Receptor Beta ELISA kit
Er-Beta ELISA kit
Nuclear Receptor Subfamily 3 Group A Member 2 ELISA kit
Esr2 ELISA kit
Erbeta ELISA kit
Nr3a2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance