| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ALDH1B1 (278-517) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ALDH1B1 |
| Gene ID: |
219 |
| Uniprot ID: |
AL1B1_HUMAN |
| Immunogen Region: |
278-517 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 278-517 of human ALDH1B1 (NP_000683.3). |
| Immunogen Sequence: |
NLKRVTLELGGKSPSIVLAD ADMEHAVEQCHEALFFNMGQ CCCAGSRTFVEESIYNEFLE RTVEKAKQRKVGNPFELDTQ QGPQVDKEQFERVLGYIQLG QKEGAKLLCGGERFGERGFF IKPTVFGGVQDDMRIAKEEI FGPVQPLFKFKKIEEVVERA NNTRYGLAAAVFTRDLDKAM YFTQALQAGTVWVNTYNIVT CHTPFGGFKESGNGRELGED GLKAYTEVKTVTIKVPQKN |
| Tissue Specificity | Liver, testis and to a lesser extent in brain. |
| Function | ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. |
| Protein Name | Aldehyde Dehydrogenase X - MitochondrialAldehyde Dehydrogenase 5Aldehyde Dehydrogenase Family 1 Member B1 |
| Database Links | Reactome: R-HSA-71384 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Aldehyde Dehydrogenase X - Mitochondrial antibodyAnti-Aldehyde Dehydrogenase 5 antibodyAnti-Aldehyde Dehydrogenase Family 1 Member B1 antibodyAnti-ALDH1B1 antibodyAnti-ALDH5 antibodyAnti-ALDHX antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
