| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-IL1F10 (1-152) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
IL1F10 |
| Gene ID: |
84639 |
| Uniprot ID: |
IL1FA_HUMAN |
| Immunogen Region: |
1-152 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human IL1F10 (NP_115945.4). |
| Immunogen Sequence: |
MCSLPMARYYIIKYADQKAL YTRDGQLLVGDPVADNCCAE KICILPNRGLARTKVPIFLG IQGGSRCLACVETEEGPSLQ LEDVNIEELYKGGEEATRFT FFQSSSGSAFRLEAAAWPGW FLCGPAEPQQPVQLTKESEP SARTKFYFEQSW |
| Tissue Specificity | Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil. |
| Function | Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2. |
| Protein Name | Interleukin-1 Family Member 10Il-1f10Family Of Interleukin 1-ThetaFil1 ThetaInterleukin-1 Hy2Il-1hy2Interleukin-1 ThetaIl-1 ThetaInterleukin-38Il-38 |
| Database Links | Reactome: R-HSA-9007892Reactome: R-HSA-9014826 |
| Cellular Localisation | CytoplasmSecretedThe Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion |
| Alternative Antibody Names | Anti-Interleukin-1 Family Member 10 antibodyAnti-Il-1f10 antibodyAnti-Family Of Interleukin 1-Theta antibodyAnti-Fil1 Theta antibodyAnti-Interleukin-1 Hy2 antibodyAnti-Il-1hy2 antibodyAnti-Interleukin-1 Theta antibodyAnti-Il-1 Theta antibodyAnti-Interleukin-38 antibodyAnti-Il-38 antibodyAnti-IL1F10 antibodyAnti-FIL1T antibodyAnti-IL1HY2 antibodyAnti-IL38 antibodyAnti-FKSG75 antibodyAnti-UNQ6119 antibodyAnti-PRO20041 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
