• Western blot analysis of extracts of various cell lines, using NPTN antibody (STJ110279) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Western blot analysis of extracts of various cell lines, using NPTN antibody (STJ110279) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-NPTN antibody (29-200) (STJ110279)

SKU:
STJ110279

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-NPTN (29-200) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NPTN
Gene ID: 27020
Uniprot ID: NPTN_HUMAN
Immunogen Region: 29-200
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 29-200 of human NPTN (NP_059429.1).
Immunogen Sequence: QNEPRIVTSEEVIIRDSPVL PVTLQCNLTSSSHTLTYSYW TKNGVELSATRKNASNMEYR INKPRAEDSGEYHCVYHFVS APKANATIEVKAAPDITGHK RSENKNEGQDATMYCKSVGY PHPDWIWRKKENGMPMDIVN TSGRFFIINKENYTELNIVN LQITEDPGEYEC
Tissue Specificity Isoform 1 is ubiquitously expressed. Isoform 2 is expressed in brain cortex and cerebellum (at protein level).
Function Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity. Also acts as a chaperone for ATP2B1.stabilizes ATP2B1 and increases its ATPase activity. Promotes localization of XKR8 at the cell membrane.
Protein Name Neuroplastin
Stromal Cell-Derived Receptor 1
Sdr-1
Database Links Reactome: R-HSA-977443
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Postsynaptic Density
Alternative Antibody Names Anti-Neuroplastin antibody
Anti-Stromal Cell-Derived Receptor 1 antibody
Anti-Sdr-1 antibody
Anti-NPTN antibody
Anti-SDFR1 antibody
Anti-SDR1 antibody

Information sourced from Uniprot.org

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