| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-P2RY12 (303-313) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
P2RY12 |
| Gene ID: |
64805 |
| Uniprot ID: |
P2Y12_HUMAN |
| Immunogen Region: |
303-313 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 303-313 of human P2RY12 (NP_795345.1). |
| Immunogen Sequence: |
KSFRNSLISML |
| Tissue Specificity | Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain. |
| Function | Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation. |
| Protein Name | P2y Purinoceptor 12P2y12Adp-Glucose ReceptorAdpg-RP2t(AcP2y(AcP2y(CycP2y12 Platelet Adp ReceptorP2y(AdpSp1999 |
| Database Links | Reactome: R-HSA-392170Reactome: R-HSA-417957Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-P2y Purinoceptor 12 antibodyAnti-P2y12 antibodyAnti-Adp-Glucose Receptor antibodyAnti-Adpg-R antibodyAnti-P2t(Ac antibodyAnti-P2y(Ac antibodyAnti-P2y(Cyc antibodyAnti-P2y12 Platelet Adp Receptor antibodyAnti-P2y(Adp antibodyAnti-Sp1999 antibodyAnti-P2RY12 antibodyAnti-HORK3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
