Anti-POP1 Antibody

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Product name Anti-POP1 Antibody
Short Description Rabbit polyclonal against POP1
Description This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants.
Applications WB
Dilution range WB 1:200 - 1:2000
Protein Name Ribonucleases P/MRP protein subunit POP1
hPOP1
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human POP1 (NP_055844.2).
Storage Instruction Store at -20C. Avoid freeze / thaw cycles.
Note For Research Use Only (RUO).
Validated Application WB
Host Rabbit
Clonality Polyclonal
Reactivity Mouse, Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene ID 10940
Gene Symbol POP1
Molecular Weight 114.709 kDa
Database Links HGNC:30129
OMIM:602486
Reactome:R-HSA-6784531
Alternative Names Ribonucleases P/MRP protein subunit POP1
hPOP1
Function Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends, Also a component of RNase MRP
Cellular Localization Nucleus, nucleolus
Swiss-Prot Key Q99575
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