• Western blot analysis of extracts of various cell lines, using PWP2 antibody (STJ27725) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-PWP2 antibody (740-919) (STJ27725)

SKU:
STJ27725

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PWP2 (740-919) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PWP2
Gene ID: 5822
Uniprot ID: PWP2_HUMAN
Immunogen Region: 740-919
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 740-919 of human PWP2 (NP_005040.2).
Immunogen Sequence: ELDTSVTPGRVREALRQQDF TRAILMALRLNESKLVQEAL EAVPRGEIEVVTSSLPELYV EKVLEFLASSFEVSRHLEFY LLWTHKLLMLHGQKLKSRAG TLLPVIQFLQKSIQRHLDDL SKLCSWNHYNMQYALAVSKQ RGTKRSLDPLGSEEEAEASE DDSLHLLGGGGRDSEEEMLA
Function Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Protein Name Periodic Tryptophan Protein 2 Homolog
Database Links Reactome: R-HSA-6790901
Reactome: R-HSA-6791226
Cellular Localisation Nucleus
Nucleolus
Alternative Antibody Names Anti-Periodic Tryptophan Protein 2 Homolog antibody
Anti-PWP2 antibody
Anti-PWP2H antibody

Information sourced from Uniprot.org

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